Yes
The Pilot, MDX and Odyssey all share the same 5-114.3mm bolt pattern. They all have 6.5" wide wheels with the MDX having 17" vs 16" for the others. They all have an overall tire diameter of about 29.1" which is the number you want to stay close to when doing +1 or +2 wheels. I believe 8.5" is the widest wheel you can go with as well.